Selected outcomes after traumatic brain injury (TBI), their assessment, and therapy
Nicole von Steinbuchel, Director of the Institute of Medical Psychology and Medical Sociology of the University Medical Center, Georg-August-University of Goettingen, Germany
The Collaborative European NeuroTrauma Effectiveness (CENTER-TBI) is a large European prospective, observational cohort study, designed to improve disease characterization, clinical, neuropsychological, and psychosocial outcome and care after traumatic brain injury (TBI). For this purpose we validated clinician-reported outcome instruments linguistically and psychometrically to assess outcome after TBI. The aim of the present talk is to summarize the most important findings on selected outcomes after TBI, their assessment, and therapy.
The talk is focusing on the clinical utility (i.e., the sensitivity) of the outcome instruments, recovery patterns of anxiety, depression, post-traumatic stress disorders, post-concussion symptoms, and disease-specific health-related quality of life (HRQOL) within one year after TBI. Also factors associated with unfavorable outcomes and therapy and rehabilitation after TBI will be tackled.
The Glasgow Outcome Scale – Extended (GOSE) followed by the physical component summary score (PCS) of the long and short version of the Short Form Health Survey (SF-36v2/12v2), the Quality of Life after Traumatic Brain Injury (QOLIBRI and its overall scale) as well as the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) are the most sensitive instruments to detect differences between patient groups based on sociodemographic, premorbid, and injury related factors.
Most outcomes showed small but significant improvement between 3 and 6 months after TBI with little change thereafter. Overall, follow-up interventions, psychiatric and psychological therapy, and rehabilitation need further development.
Short Bio
Prof. Dr. Nicole von Steinbuechel
Institute of Medical Psychology and Medical Sociology
Short-Biography
Since 2004, Prof. Dr. Nicole von Steinbuechel is director of the Institute of Medical Psychology and Medical Sociology of the University Medical Center, Georg-August-University of Goettingen.
2001-2004 Associate Professor of Gerontopsychology at Geneva University and Head of the Neurogerontopsychology Unit, Department of Psychogeriatrics, Geneva University Hospital, Switzerland
1999-2000 Research Professor of the Dorothea-Erxleben Foundation, Magdeburg University, Germany
1993-1997 Professor of Medical Psychology, Institute of Medical Psychology (IMP), Ludwig Maximilians University of Munich (LMU)
1987-1993 Graduation (Dr. rer. biol. hum.) and scientific researcher at the IMP, LMU
1985 Diploma in psychology, philosophy, and history of art at the Institute of Psychology, LMU, Munich, Germany
Main areas of work (Selection): Neuropsychology (aging, dementia, stroke, TBI), cognition, health-related quality of life research (intercultural), outcome work package leader of the EU-project CENTER-TBI (5000 patients after TBI), project leader of the Quality Of Life after Brain Injury in children, adolescents (QOLIBRI-Kiddy/Kid/Ado) and adults projects.
Offices (Selection)
1998-2002 Vice-Chair of the German Society of Medical Psychology
2001-2005 Board member of the Swiss Society of Psychology
Since 2003 Board vice-treasurer of the Academia Multidisciplinaria Neurotraumatologica (AMN)
2007-2010 Board member of the European Brain and Behaviour Society (Scientific Committee)
2008 Founding member of the International Society for Clinical Neuromusicology
2008-2011 President of the QOLIBRI Society
2016-2018 President of the AMN
Since 2021 Board member of the administration of the Senkenberg`sche Foundation
Current projects (Selection)
2017-2024 “International development of an instrument for the assessment of quality of life after traumatic brain injury, QOLIBRI-KIDS/ADOS (Quality of Life after Brain Injury /Kids and Adolescents), for self-report and proxy report by affected children, adolescents and their relatives” Dr. Senckenbergische, Dr. Christ’sche Stiftung, Unscientia Vaduz, Deutsche gesetzliche Unfallversicherung
2013-2020 Work Package Leader: EU-Health 2013.2.2.1-1: Prospective longitudinal data collection and Comparative Effectiveness Research (CER) for traumatic brain injury (TBI). Assessment and Classification of outcome: Towards a multi-dimensional approach. FP7-Health-2013-Innovation 1
